Guillaume LEBRETON
Department of Cardiac Surgery
Pitie-Salpetriere Hospital, Sorbonne University
47-83 Boulevard de l’Hopital, 75013 Paris, France
RPPS : 10100164515
CERTIFICATIONS & LICENSES
2020 « Habilitation à diriger les recherches » (French Post-Doctoral Degree)
2018 PhD of Sorbonne University, Paris, France
2014 Diploma of the French College of Thoracic & Cardio-Vascular Surgery
2013 Lecturer competition - Associate professor
2013 Diploma of Thoracic & Cardiovascular Surgery
2010 Diploma of General Surgery
2010 MD with distinctions. FWI University / Pitie-Salpêtrière. Paris VI University
2009 Master 2 Surgical Sciences. Paris XII University
Diploma of Extracorporeal circulation & organs support, of Circulatory Support, of Microsurgery, & of Surgical Emergencies.
PROFESSIONAL EXPERIENCE
2013-2021 Associate Professor. Thoracic & Cardiovascular Surgery. Sorbonne University
2012-2021 Thoracic & Cardiovascular Surgeon. Pitie-Salpetriere Hospital, Paris France
2012-2021 Head of CPB & ECMO programs, Pitie-Salpetriere Hospital, Paris
2010-2012 Thoracic & Cardiovascular Surgeon. University Hospital of Martinique, France
ACTIVITIES
ADULT CARDIAC SURGERY
Adult cardiac surgery (Valvular surgery, Aortic surgery, CABG,…)
Heart transplantation
Mechanical circulatory support, ECMO
EDUCATION
Education at the medical school of Sorbonne University
Director of the valvular surgery & VAD diplomas, Sorbonne University
Director of the Master of perfusion, Sorbonne University
Board of directors of the ECMO diploma, Sorbonne University
RESEARCH
Inserm UMR 1166 – Sorbonne Univerity
Investigator of Euroscore II, Euroscore bio, EOLIA trial, ANCHOR trial, CADENCE trial, PHAM trial, …
PROFESSIONAL ASSOCIATIONS & SOCIETIES
2019 Member of the National Council of the Universities (CNU)
2018 Board of the European Society of Mechanical Support EUMS
2014 Board of the French Society of Perfusion. SOFRAPERF
2012 Board of French Society of Thoracic & Cardiovascular Surgery SFCTCV
2012 Member of the French Agency of Transplantion (ABM)
2012 Member of the European Association of Cardio Thoracic Surgery EACTS
Guillaume LEBRETON, MD, PhD - Curriculum Vitae – december 2021
PUBLICATIONS
159 publications internationales (indexées Pubmed): 33 rank A, 51 rank B, 33 rank C.
Score SIGAPS = 1688. 62 international & 68 national invited lectures.
Main recent publications:
Giangreco NP, Lebreton G, Restaino S, Jane Farr M, Zorn E, Colombo PC, Patel J, Levine R, Truby L, Soni RK, Leprince P, Kobashigawa J, Tatonetti NP, Fine BM. Plasma kallikrein predicts primary graft dysfunction after heart transplant. J Heart Lung Transplant. 2021 Oct;40(10).
Lebreton G, Dorgham K, Quentric P, Combes A, Gorochov G, Schmidt M. Longitudinal Cytokine Profiling in Patients with Severe COVID-19 on Extracorporeal Membrane Oxygenation and Hemoadsorption. Am J Respir Crit Care Med. 2021 Jun 1;203(11).
Lebreton G, Schmidt M, Ponnaiah M, et al; Paris ECMO-COVID-19 investigators. ECMO network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort study. Lancet Respir Med. 2021 Aug;9(8):851-862.
Schmidt M, Hajage D, Lebreton G, et al; Paris-Sorbonne ECMO-COVID investigators. ECMO for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study. Lancet Respir Med. 2020 Nov;8(11):1121-1131.
Lebreton G, Al Kalbani H, Juvin C, Leprince P. Transitioning to total artificial heart for patients supported with short term mechanical circulatory devices. Ann Cardiothorac Surg. 2020 mar.
David CH, Quessard A, Mastroianni C, Hekimian G, Amour J, Leprince P, Lebreton G. Mechanical circulatory support with the Impella 5.0 pumps for postcardiotomy cardiogenic shock at La Pitié-Salpêtrière Hospital., Eur J Cardiothorac Surg, 2020, 57, 183-188
Coutance G, Jacob N, Demondion P, Nguyen LS, Bouglé A, Bréchot N, Varnous S, Leprince P, Combes A, Lebreton G. Favorable Outcomes of a Direct Heart Transplantation Strategy in Selected Patients on Extracorporeal Membrane Oxygenation Support., Crit Care Med, 2019
Colombier S, Quessard A, Mastroianni C, Schmidt M, Amour J, Leprince P, Lebreton G. Benefits of Impella and Peripheral Veno-Arterial Extra Corporeal Life Support Alliance. ASAIO J. 2018 Dec 11.
Danial P, Hajage D, Nguyen LS, Mastroianni C, Demondion P, Schmidt M, Bouglé A, Amour J, Leprince P, Combes A, Lebreton G. Percutaneous versus surgical femoro-femoral veno-arterial ECMO: a propensity score matched study. Intensive Care Med. 2018 Dec;44(12).
Lebreton G, Mastroianni C, Amour J, Leprince P. Implantation of Two HVADs Used as a Total Artificial Heart. Ann Thorac Surg. 2018 Sep 25.
Combes A, Hajage D, Capellier G, Demoule A, Lavoué S, Guervilly C, Da Silva D, Zafrani L, Tirot P, Veber B, Maury E, Levy B, Cohen Y, Richard C, Kalfon P, Bouadma L, Mehdaoui H, Beduneau G, Lebreton G, Brochard L, Ferguson ND, Fan E, Slutsky AS, Brodie D, Mercat A; EOLIA Trial Group, REVA, and ECMONet. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome. N Engl J Med. 2018 May 24;378(21):1965-1975.
Mebazaa A, Combes A, van Diepen S, Hollinger A, Katz JN, Landoni G, Hajjar LA, Lassus J, Lebreton G, Montalescot G, et al. Management of cardiogenic shock complicating myocardial infarction. Intensive Care Med. 2018 May 16.
Galeone A, Varnous S, Lebreton G, Barreda E, Hariri S, Pavie A, Leprince P. Impact of cardiac arrest resuscitated donors on heart transplant recipients 'outcome. J Thorac Cardiovasc Surg. 2017 Mar;153(3):622-630.
Jasseron C, Lebreton G, Cantrelle C, Legeai C, Leprince P, Flecher E, Sirinelli A, Bastien O, Dorent R. Impact of Heart Transplantation on Survival in Patients on VA-ECMO at Listing in France. Transplantation. 2016 Sep;100(9):1979-87.
Pitie-Salpetriere Hospital, Sorbonne University
47-83 Boulevard de l’Hopital, 75013 Paris, France
RPPS : 10100164515
CERTIFICATIONS & LICENSES
2020 « Habilitation à diriger les recherches » (French Post-Doctoral Degree)
2018 PhD of Sorbonne University, Paris, France
2014 Diploma of the French College of Thoracic & Cardio-Vascular Surgery
2013 Lecturer competition - Associate professor
2013 Diploma of Thoracic & Cardiovascular Surgery
2010 Diploma of General Surgery
2010 MD with distinctions. FWI University / Pitie-Salpêtrière. Paris VI University
2009 Master 2 Surgical Sciences. Paris XII University
Diploma of Extracorporeal circulation & organs support, of Circulatory Support, of Microsurgery, & of Surgical Emergencies.
PROFESSIONAL EXPERIENCE
2013-2021 Associate Professor. Thoracic & Cardiovascular Surgery. Sorbonne University
2012-2021 Thoracic & Cardiovascular Surgeon. Pitie-Salpetriere Hospital, Paris France
2012-2021 Head of CPB & ECMO programs, Pitie-Salpetriere Hospital, Paris
2010-2012 Thoracic & Cardiovascular Surgeon. University Hospital of Martinique, France
ACTIVITIES
ADULT CARDIAC SURGERY
Adult cardiac surgery (Valvular surgery, Aortic surgery, CABG,…)
Heart transplantation
Mechanical circulatory support, ECMO
EDUCATION
Education at the medical school of Sorbonne University
Director of the valvular surgery & VAD diplomas, Sorbonne University
Director of the Master of perfusion, Sorbonne University
Board of directors of the ECMO diploma, Sorbonne University
RESEARCH
Inserm UMR 1166 – Sorbonne Univerity
Investigator of Euroscore II, Euroscore bio, EOLIA trial, ANCHOR trial, CADENCE trial, PHAM trial, …
PROFESSIONAL ASSOCIATIONS & SOCIETIES
2019 Member of the National Council of the Universities (CNU)
2018 Board of the European Society of Mechanical Support EUMS
2014 Board of the French Society of Perfusion. SOFRAPERF
2012 Board of French Society of Thoracic & Cardiovascular Surgery SFCTCV
2012 Member of the French Agency of Transplantion (ABM)
2012 Member of the European Association of Cardio Thoracic Surgery EACTS
Guillaume LEBRETON, MD, PhD - Curriculum Vitae – december 2021
PUBLICATIONS
159 publications internationales (indexées Pubmed): 33 rank A, 51 rank B, 33 rank C.
Score SIGAPS = 1688. 62 international & 68 national invited lectures.
Main recent publications:
Giangreco NP, Lebreton G, Restaino S, Jane Farr M, Zorn E, Colombo PC, Patel J, Levine R, Truby L, Soni RK, Leprince P, Kobashigawa J, Tatonetti NP, Fine BM. Plasma kallikrein predicts primary graft dysfunction after heart transplant. J Heart Lung Transplant. 2021 Oct;40(10).
Lebreton G, Dorgham K, Quentric P, Combes A, Gorochov G, Schmidt M. Longitudinal Cytokine Profiling in Patients with Severe COVID-19 on Extracorporeal Membrane Oxygenation and Hemoadsorption. Am J Respir Crit Care Med. 2021 Jun 1;203(11).
Lebreton G, Schmidt M, Ponnaiah M, et al; Paris ECMO-COVID-19 investigators. ECMO network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort study. Lancet Respir Med. 2021 Aug;9(8):851-862.
Schmidt M, Hajage D, Lebreton G, et al; Paris-Sorbonne ECMO-COVID investigators. ECMO for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study. Lancet Respir Med. 2020 Nov;8(11):1121-1131.
Lebreton G, Al Kalbani H, Juvin C, Leprince P. Transitioning to total artificial heart for patients supported with short term mechanical circulatory devices. Ann Cardiothorac Surg. 2020 mar.
David CH, Quessard A, Mastroianni C, Hekimian G, Amour J, Leprince P, Lebreton G. Mechanical circulatory support with the Impella 5.0 pumps for postcardiotomy cardiogenic shock at La Pitié-Salpêtrière Hospital., Eur J Cardiothorac Surg, 2020, 57, 183-188
Coutance G, Jacob N, Demondion P, Nguyen LS, Bouglé A, Bréchot N, Varnous S, Leprince P, Combes A, Lebreton G. Favorable Outcomes of a Direct Heart Transplantation Strategy in Selected Patients on Extracorporeal Membrane Oxygenation Support., Crit Care Med, 2019
Colombier S, Quessard A, Mastroianni C, Schmidt M, Amour J, Leprince P, Lebreton G. Benefits of Impella and Peripheral Veno-Arterial Extra Corporeal Life Support Alliance. ASAIO J. 2018 Dec 11.
Danial P, Hajage D, Nguyen LS, Mastroianni C, Demondion P, Schmidt M, Bouglé A, Amour J, Leprince P, Combes A, Lebreton G. Percutaneous versus surgical femoro-femoral veno-arterial ECMO: a propensity score matched study. Intensive Care Med. 2018 Dec;44(12).
Lebreton G, Mastroianni C, Amour J, Leprince P. Implantation of Two HVADs Used as a Total Artificial Heart. Ann Thorac Surg. 2018 Sep 25.
Combes A, Hajage D, Capellier G, Demoule A, Lavoué S, Guervilly C, Da Silva D, Zafrani L, Tirot P, Veber B, Maury E, Levy B, Cohen Y, Richard C, Kalfon P, Bouadma L, Mehdaoui H, Beduneau G, Lebreton G, Brochard L, Ferguson ND, Fan E, Slutsky AS, Brodie D, Mercat A; EOLIA Trial Group, REVA, and ECMONet. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome. N Engl J Med. 2018 May 24;378(21):1965-1975.
Mebazaa A, Combes A, van Diepen S, Hollinger A, Katz JN, Landoni G, Hajjar LA, Lassus J, Lebreton G, Montalescot G, et al. Management of cardiogenic shock complicating myocardial infarction. Intensive Care Med. 2018 May 16.
Galeone A, Varnous S, Lebreton G, Barreda E, Hariri S, Pavie A, Leprince P. Impact of cardiac arrest resuscitated donors on heart transplant recipients 'outcome. J Thorac Cardiovasc Surg. 2017 Mar;153(3):622-630.
Jasseron C, Lebreton G, Cantrelle C, Legeai C, Leprince P, Flecher E, Sirinelli A, Bastien O, Dorent R. Impact of Heart Transplantation on Survival in Patients on VA-ECMO at Listing in France. Transplantation. 2016 Sep;100(9):1979-87.